Used to facilitate rape (it is odorless and tasteless, therefore it can be slipped into someone's drink without detection) because it causes impairments in judgment, sleepiness and amnesia.

Liver failure  

Seizures which can result in coma and even death

Respiratory failure and/or arrest

Severe nausea and vomiting

When ingested in conjunction with alcohol or other drugs, effects begin within 3 minutes and peak within 2 hours. These effects may persist for up to 8 hours or more, depending upon the dosage.

Adverse effects associated with the use of Rohypnol include decreased blood pressure, memory impairment, drowsiness, visual disturbances, dizziness, confusion, gastrointestinal disturbances, and urinary retention.

Psychological difficulties, including confusion, depression, sleep problems, drug craving, severe anxiety and paranoia

Muscle tension, involuntary teeth clenching, nausea, blurred vision, rapid eye movement, faintness, and chills or swelling

Increased heart rate and blood pressure

Long-term brain damage

Symptoms of stimulant abuse include increased heart and respiratory rates, elevated blood pressure, dilated pupils, excessive perspiration, headache, dizziness, sleepiness, anxiety, and loss of appetite.

When consumed in large quantities, palpitations, irregular heartbeat, tremors, loss of coordination, coma, and death may result.

Regular use can lead to an amphetamine psychosis that includes hallucinations, delusions, and paranoia.

Narcotics initially produce a feeling of euphoria followed by drowsiness, nausea, and vomiting.

Users may experience constricted pupils, watery eyes, and itching.

An overdose may produce slow and shallow breathing, clammy skin, convulsions, coma, and death.

Tolerance to narcotics develops rapidly and dependence is likely.

Intravenous injection may cause HIV/AIDS, hepatitis, and cardiac disease.

Addiction in pregnant women can lead to premature, stillborn, or addicted infants who may exhibit withdrawal symptoms.

Liver disease

Growth problems

Bone fusion

Acne

Cancer

Testicular atrophy

HIV/AIDS (sharing needles)

Psychological problems

Rage and uncontrolled anger

Sexual dysfunction, sterility and impotence

Immediate effects of inhalants include nausea, sneezing, coughing, nosebleed, fatigue, lack of coordination, and loss of appetite. They may also obstruct airways causing death.

Solvents and aerosol sprays may decrease heart and respiratory rates and impair judgment.

Amyl and butyl nitrate cause rapid pulse, headaches, and urinary and fecal incontinence.

Long-term use may result in hepatitis, brain damage, weight loss, fatigue, electrolyte imbalance, and muscle weakness.

Repeated use of inhalants may permanently damage the nervous system.

Cocaine stimulates the central nervous system and its immediate effects include elevated blood pressure, heart rate, respiratory rate, and body temperature.

Occasional use can cause a runny nose while chronic use can result in ulceration and rupture of the mucous membrane in the nose.

Injecting cocaine with contaminated needles can transmit HlV/AIDS, hepatitis, and other infectious diseases.

Cocaine use may lead to high-risk behaviors with consequences such as unwanted pregnancies and motor vehicle accidents.

Cocaine use during pregnancy may result in the birth of a cocaine-addicted baby who may experience withdrawal symptoms shortly after birth, mental retardation, and/or permanent mental and physical disabilities.

Crack, a concentrated form of cocaine, is extremely potent. Its effects are evident within seconds. Physical effects include heart palpitations, elevated pulse and blood pressure, loss of appetite, insomnia, dilated pupils, tactile hallucinations, paranoia, and seizures. Preparation of free-base, which involves the use of highly volatile solvents, can result in a fire or explosion. Dependency is highly likely.

The use of depressants can cause both physical and psychological dependence. Tolerance may result after regular use. Withdrawal symptoms, ranging from anxiety to seizures and death, result from abrupt termination of abuse.

Women who abuse depressants during pregnancy may give birth to babies who are physically dependent. These babies often have birth defects, behavioral problems, and may develop withdrawal symptoms shortly after birth.

Large doses can cause slurred speech, impaired coordination, and altered perception. Very large doses can cause respiratory depression, coma, and death. Even small doses of depressants, when combined with alcohol, are likely to produce the symptoms described above.

The effects associated with marijuana use include:

An increase in heart rate and blood pressure, blood-shot eyes, dry mouth, and hunger.

Impairment of short-term memory and concentration, altered sense of time, and decreased coordination and motivation.

Psychological dependence.

Lung cancer, and chronic lung disease after long-term use.